A UFC Heavyweight Championship bout between Francis Ngannou and champion Stipe Miocic served as If headliner.

[3]
The event also featured a UFC Light Heavyweight Championship bout between present champion Daniel Cormier and Volkan Oezdemir. [4]
A welterweight bout between The Ultimate Fighter: American Top Team vs. Blackzilians welterweight winner Kamaru Usman and Emil Weber Meek was originally scheduled for UFC 219. But because of an alleged visa issue for Meek which affected his traveling program, the pairing was postponed and then rescheduled to this particular occasion. [5] However, it was changed to UFC Fight Night: Stephens vs. Choi per day later, which took place six days prior to this event. [6]
A welterweight bout between Abdul Razak Alhassan and Sabah Homasi was originally scheduled for UFC 219, but later shifted to this event. When Alhassan acquired via a TKO, the pairing met previously at UFC 218. [7][8]
Charles Rosa was expected to face promotional novice Dan Ige in the event. On December 22, Rosa pulled due to a neck injury. [9] Ige stayed on the card and faced fellow newcomer Julio Arce. [10]
Arnold Allen was anticipated to confront The Ultimate Fighter: Latin America 2 lightweight winner Enrique Barzola in the occasion. But, Allen was pulled in the fight on January 11 due to alleged visa issues which limited his ability to travel. [11] He was substituted by novice Matt Bessette that is promotional. [12]
Jamie Moyle was anticipated to confront Maryna Moroz in the occasion. But, Moyle pulled from the fight during the week leading up to case citing an undisclosed injury. [13] In turn, promotion officials indicated that Moroz would be rescheduled for a future occasion.

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